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Research Library

As‑One‑Goes Blood Pressure and Heart Rate Monitoring: A Chronobiology Approach with Applications in Clinical Practice and Basic Science

    • Published: 2021
    • Germaine Cornelissen1, Yoshihiko Watanabe2, Larry A. Beaty1, A. Chase Turner1, Robert Sothern1, Jarmila Siegelova3, Tamara Breus4, Denis Gubin5, Abdullah A. Alabdulgader6, Rollin McCraty7, and Kuniaki Otsuka1,8
    • Cardiol Vasc Res. 2021; 5(1): 1-10. ISSN: 2639-8486.1. Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN, USA.2. Women’ s Medical University, Tokyo, Japan.3. Masaryk University, Brno, Czech Republic.4. Space Research Institute, Russian Academy of Sciences, Moscow, Russia.5. Medical University, Tyumen, Russia.6. Prince Sultan Cardiac Center, Al Ahsa, Saudi Arabia.7. Institute of HeartMath, Boulder Creek, CA, USA.8. Executive Medical Center, Totsuka Royal Clinic, Tokyo Women’ s Medical University, Tokyo, Japan.
    • Download the complete paper, click here.


Assessing influences of space weather on human physiology often relies on correlations between the socio-biological variable and the environment. One major pitfall of such an approach is the disregard for periodicities characterizing both biology and nature, many of them shared between the two systems. Alternative, more robust analytical techniques of time series analysis, such as those used in chronobiology, are better suited to avoid spurious results. Blood pressure and heart rate are highly variable along several time scales, ranging from the fast oscillations of the brain and heart to the multi-decadal cycles associated with changes in solar activity. Since these variables can be easily monitored longitudinally, they lend themselves well to the study of helio-geomagnetic effects from a basic science viewpoint. At the same time, such physiological monitoring offers useful clinical applications.