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This article proposes HeartMath as a positive psychology paradigm for promoting psychophysiological and global coherence. It provides evidence for the value of psychophysiological and global coherence, with special reference to human functioning through synchronisation between positive emotions, cardiovascular, respiratory, nervous, immune and other physiological systems. Various HeartMath tools and techniques are described and evidence for their effectiveness provided, drawing from several related South African studies. Psychophysiological and global coherence bear promise as fertile fields for future research and intervention of great potential to develop humanity and promote global health and wellbeing.